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Belonging to the biguanide class of medicines, metformin is the number one treatment drug of doctors when it comes to treating diabetes especially in overweight and obese people and also those with normal kidney function.
Metformin as a powerful diab etes drug is known to reduce blood sugar levels by bringing down the amount of sugar produced in the liver along with reducing the amount of glucose absorbed through the stomach. This not only makes metformin a wonderful dieting aid for obese and over-weight people but also act as anti ageing supplement for those with cardiovascular problem by lowering the cholesterol levels in the blood.
Insulin is a hormone produced in the pancreatic glands of our body and is essential to not only reduce glucose levels produced by our liver but also in removing glucose from the blood by muscle and fat tissues which burn glucose for energy. Diabetes is caused when this amount of insulin produced in our pancreatic glands suddenly reduces or when the cells of our body become resistant to the action of insulin, thereby making it necessary to seek proper treatment or solution.
Insulin resistance is a serious condition which not only causes type 2 diabetes in individuals but is also responsible for myriad other disorders of the body such as cardiovascular disease, obesity and PCOS in women of reproductive age. While there are many other type 2 diabetes treatment drugs and glucose lowering drugs available in the market, what makes metformin superior and safer for type 2 diabetes treatment over these insulin resistance treatment drugs is its method of action.
Metformin works by making the receptors more sensitive to insulin which means available glucose is utilized more effectively, unlike other glucose lowering drugs like Glyburide (Micronase, Diabeta) or Glipizide (Glucotrol), which increase the level of insulin in the blood and as a result, cause excessively low blood glucose levels. Metformin on the other hand, doesn't reduce the availability of glucose within the body, and doesn't affect the levels of insulin.
Moreover, as an anti ageing supplement, metformin increases the sensitivity of the hypothalamus and peripheral tissues (like muscles) to the effects of insulin. In effect, it rejuvenates this response, restoring the effects of glucose and insulin to much younger physiological levels.
Metformin Metforal is a completely safe medicine with no known contraindications or toxicity. However, people with kidney problem are advised to seek doctor approval before taking this medicine. Recommended dosage for people over 40 years of age is 500mg to 850mg – up to three times a day..